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Han legger til at i sjeldne tilfeller kan male få komplekst regional smertesyndrom. Da vil smerten utvide seg og omfatte en større del.Der er ingen bivirkninger ved behandlingen med paracetamol, hvis male holder sig til below fireplace gram i døgnet. Dog kan nogle mennesker udvikle hovedpine ved længere tids brug.Har formentlig en dobbeltvirken